Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area
نویسندگان
چکیده
منابع مشابه
Thyroid hormone insufficiency during brain development reduces parvalbumin immunoreactivity and inhibitory function in the hippocampus.
Thyroid hormones are necessary for brain development. gamma-Amino-butyric acid (GABA)ergic interneurons comprise the bulk of local inhibitory circuitry in brain, many of which contain the calcium binding protein, parvalbumin (PV). A previous report indicated that severe postnatal hypothyroidism reduces PV immunoreactivity (IR) in rat neocortex. We examined PV-IR and GABA-mediated synaptic inhib...
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ژورنال
عنوان ژورنال: Journal of Neuroendocrinology
سال: 2018
ISSN: 0953-8194
DOI: 10.1111/jne.12573